Design and Analysis of 2D Photonic Crystal-Based Biosensor for Cancerous Cell Detection

This paper presents a new design of a biosensor, aiming to detect cancerous cells, based on a two-dimensional silicon-rods-in-air photonic crystal (PhC) nanocavity. The impact of radius-variation of the nanocavity-rods on the biosensor characteristics has been examined. A sensitivity of 600 nm/RIU and quality factor of 3835.9 were achieved, resulting in a low detection limit of <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">$6.36\times 10^{-5}$</tex> RIU and a high Figure of Merit of 1572.094 RIU<sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">−1</sup>• Therefore, the proposed structure can be utilized for various medical diagnostic applications including label-free detection of cancerous cells.