[Electroacupuncture improves cognitive function by modulating hippocampal lactate-mediated HIF-1α signaling pathway and inhibiting inflammation response in vascular dementia rats].

EA stimulation of EX-HN1 and GB20 can improve the cognitive function in VD rats, which may be related to its functions in reducing Lac content, regulating the expression of HIF-1α pathway related proteins, and inhibiting inflammatory responses in the hippocampus tissue.

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Publication Details

Journal
PubMed
Published
2024-10-25
DOI
https://doi.org/10.13702/j.1000-0607.20240296
Citations
1
Primary Topic
Neurological Disease Mechanisms and Treatments
Type
article
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article

[Electroacupuncture improves cognitive function by modulating hippocampal lactate-mediated HIF-1α signaling pathway and inhibiting inflammation response in vascular dementia rats].

Hong Zhao, Yuanjian Song, Ruiqi Qin, Haoyu Wang et al.
1 citations
PubMed
Neurological Disease Mechanisms and Treatments
article

[Electroacupuncture improves cognitive function by modulating hippocampal lactate-mediated HIF-1α signaling pathway and inhibiting inflammation response in vascular dementia rats].

Hong Zhao, Yuanjian Song, Ruiqi Qin, Haoyu Wang, Junfeng Li, Yusheng Han, Yinghua Chen, Tong Wu, Wei Sun, Xiaoqing Su
article en
1 citations

Abstract

EA stimulation of EX-HN1 and GB20 can improve the cognitive function in VD rats, which may be related to its functions in reducing Lac content, regulating the expression of HIF-1α pathway related proteins, and inhibiting inflammatory responses in the hippocampus tissue.

PubMedVol. 49(10)
Heilongjiang University of Chinese Medicine (CN)
Neurological Disease Mechanisms and Treatments
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