Impact of rapid blood culture identification PCR panel on optimal antibiotic use in methicillin-susceptible <i>Staphylococcus aureus</i> bacteremia

In this retrospective study of 200 patients with methicillin-susceptible <i>Staphylococcus aureus</i> (MSSA) bacteremia, the implementation of the BioFire® blood culture identification polymerase chain reaction (PCR) panel was associated with a decreased time to optimal MSSA antibiotic therapy and shorter durations of empiric anti-MRSA antibiotic therapy and bacteremia. The findings demonstrate the significant role of rapid PCR testing and routine stewardship review in optimizing antimicrobial therapy and management of MSSA bacteremia.

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Publication Details

Journal
Microbiology Spectrum
Published
2024-10-22
DOI
https://doi.org/10.1128/spectrum.00629-24
Citations
4
Primary Topic
Bacterial Identification and Susceptibility Testing
Type
article
Field-Weighted Citation Impact
1.52
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article

Impact of rapid blood culture identification PCR panel on optimal antibiotic use in methicillin-susceptible Staphylococcus aureus bacteremia

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4 citations
Microbiology Spectrum
Bacterial Identification and Susceptibility Testing
1.52
article

Impact of rapid blood culture identification PCR panel on optimal antibiotic use in methicillin-susceptible Staphylococcus aureus bacteremia

Dimple Patel, Robert Roland, Pamela Giordano, Jahnavi Yetukuri, Aiman Bandali, Jason Kessler
article en
4 citations

Abstract

In this retrospective study of 200 patients with methicillin-susceptible <i>Staphylococcus aureus</i> (MSSA) bacteremia, the implementation of the BioFire® blood culture identification polymerase chain reaction (PCR) panel was associated with a decreased time to optimal MSSA antibiotic therapy and shorter durations of empiric anti-MRSA antibiotic therapy and bacteremia. The findings demonstrate the significant role of rapid PCR testing and routine stewardship review in optimizing antimicrobial therapy and management of MSSA bacteremia.

Microbiology SpectrumVol. 12(12)
Rutgers, The State University of New Jersey (US), Overlook Medical Center (US), Morristown Medical Center (US), Rutgers Sexual and Reproductive Health and Rights (NL)
Good health and well-being
Openalex Percentile: Top 18%
Bacterial Identification and Susceptibility Testing
1.52
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