Pregnancy After Beating Thyroid Cancer: A Case Series

Thyroid cancer is common among women of reproductive age and is a frequently occurring cancer during pregnancy, following breast cancer. Contributing factors include radiation exposure, iodine deficiency, and genetic conditions like multiple endocrine neoplasia type 2 (MEN2). Pregnancy significantly impacts thyroid function, leading to gland enlargement and altered thyroid stimulating hormone (TSH) levels due to hormonal changes, including elevated human chorionic gonadotropin (hCG) and estrogen. When differentiated thyroid cancer (DTC), particularly papillary thyroid carcinoma (PTC), is diagnosed during pregnancy or shortly after, careful management is essential. Treatment usually involves total thyroidectomy, with radioactive iodine therapy delayed until after childbirth. A review of cases indicates that women with PTC can have successful pregnancies with close medical supervision. Despite the complexities of cancer treatment during pregnancy, outcomes for both mother and baby are generally positive. These cases emphasize the importance of a collaborative approach in managing thyroid cancer during pregnancy and highlight the need for further research to optimize treatment and outcomes for both mother and child.

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Publication Details

Journal
Cureus
Published
2024-10-22
DOI
https://doi.org/10.7759/cureus.72122
Primary Topic
Thyroid Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Pregnancy After Beating Thyroid Cancer: A Case Series

Tharaka Senathirajah, Shanthi Ethirajan, Shruti Ganti, Jayashree Srinivasan
Cureus
Thyroid Cancer Diagnosis and Treatment
article

Pregnancy After Beating Thyroid Cancer: A Case Series

Tharaka Senathirajah, Shanthi Ethirajan, Shruti Ganti, Jayashree Srinivasan
article en

Abstract

Thyroid cancer is common among women of reproductive age and is a frequently occurring cancer during pregnancy, following breast cancer. Contributing factors include radiation exposure, iodine deficiency, and genetic conditions like multiple endocrine neoplasia type 2 (MEN2). Pregnancy significantly impacts thyroid function, leading to gland enlargement and altered thyroid stimulating hormone (TSH) levels due to hormonal changes, including elevated human chorionic gonadotropin (hCG) and estrogen. When differentiated thyroid cancer (DTC), particularly papillary thyroid carcinoma (PTC), is diagnosed during pregnancy or shortly after, careful management is essential. Treatment usually involves total thyroidectomy, with radioactive iodine therapy delayed until after childbirth. A review of cases indicates that women with PTC can have successful pregnancies with close medical supervision. Despite the complexities of cancer treatment during pregnancy, outcomes for both mother and baby are generally positive. These cases emphasize the importance of a collaborative approach in managing thyroid cancer during pregnancy and highlight the need for further research to optimize treatment and outcomes for both mother and child.

CureusVol. 16(10)
Saveetha University (IN)
Good health and well-being
Openalex Percentile: Top 70%
Thyroid Cancer Diagnosis and Treatment
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