Qualitative drivers of postoperative prophylactic antibiotics use and resistance in Ethiopia
Study participants perceived that existing evidence and guidelines did not apply in their settings due to high rates of surgical site infections and gaps in perioperative IPC practices (e.g., availability of water for handwashing, sterility breaches). These gaps were a key contributor to prophylactic antibiotic overprescribing, reinforcing the need to strengthen upstream and perioperative surgical antisepsis processes. The findings of this study underscore the importance of engaging multidisciplinary teams in strengthening antimicrobial stewardship efforts, aligning processes to achieve compliance with best practices, and the need for rigorous, contextually appropriate studies from these settings to inform policy.
Authors
- Natnael Atnafu Gebeyehu (ORCID: https://orcid.org/0000-0001-9583-833X)
- Samantha Steeman (ORCID: https://orcid.org/0000-0002-2889-2683)
- Sylvia Bereknyei Merrell (ORCID: https://orcid.org/0000-0002-5525-0379)
- Tihitena Negussie Mammo (ORCID: https://orcid.org/0000-0003-3730-4246)
- Maia R. Nofal (ORCID: https://orcid.org/0000-0003-2532-4514)
- Thomas G. Weiser (ORCID: https://orcid.org/0000-0002-3118-3888)
- Assefa Tesfaye (ORCID: https://orcid.org/0009-0007-3462-4056)
- Alex Zhuang
- Ibrahim Heyredin
- Hailemichael Asmamaw
Institutions
- Boston University (US)
- Boston Medical Center (US)
- Center for Health and Gender Equity (US)
- International Trachoma Initiative (ET)
- Tikur Anbessa Hospital (ET)
- Addis Ababa University (ET)
- Fogarty International Center (US)
- Stanford University (US)
Publication Details
- Journal
- BMC Health Services Research
- Published
- 2024-10-22
- DOI
- https://doi.org/10.1186/s12913-024-11650-4
- Citations
- 4
- Primary Topic
- Antibiotic Use and Resistance
- Type
- article
- Field-Weighted Citation Impact
- 1.19
Funders
- Northwestern University
- National Institutes of Health
- Fogarty International Center
- Stanford University Center for Innovation in Global Health