Fifteen Years of Neonatal Therapeutic Hypothermia: Clinical Trends Show Unchanged Post-Rewarming Outcomes despite Reduction in Hypoxic-Ischemic Encephalopathy Severity
Over the last 15 years, we treated more infants with milder HIE, as indicated by lower Thompson and milder aEEG scores, and the need for invasive cardiorespiratory support declined. However, there were no improvements in composite adverse outcome (mortality and/or adverse MRI score).
Authors
- Andrea van Steenis (ORCID: https://orcid.org/0000-0002-0549-7066)
- Linda S. de Vries (ORCID: https://orcid.org/0000-0002-7282-8304)
- Sylke Jeanne Steggerda (ORCID: https://orcid.org/0000-0002-5603-5697)
- Floris Groenendaal (ORCID: https://orcid.org/0000-0002-9284-1637)
- Bregje O. van Oldenmark (ORCID: https://orcid.org/0009-0002-4701-1543)
Institutions
- Utrecht University (NL)
- Leiden University Medical Center (NL)
- University Medical Center Utrecht (NL)
- Wilhelmina Children's Hospital (NL)
Publication Details
- Journal
- Neonatology
- Published
- 2024-10-22
- DOI
- https://doi.org/10.1159/000541472
- Citations
- 5
- Primary Topic
- Neonatal and fetal brain pathology
- Type
- article
- Field-Weighted Citation Impact
- 5.55
Funders
- Universiteit Leiden
- Leids Universitair Medisch Centrum