Species Differences in Ezetimibe Glucuronidation
The study revealed that the rate of ezetimibe glucuronidation in the intestine was different in different species and has an impact on ezetimibe glucuronidation in the intestine. When analyzing the pharmacodynamics, pharmacokinetics, or toxicology of ezetimibe using different models, these species differences must be taken into consideration.
Authors
- Dong Liang (ORCID: https://orcid.org/0000-0001-6632-8066)
- Huan Xie (ORCID: https://orcid.org/0000-0002-0591-5619)
- Ting Du (ORCID: https://orcid.org/0000-0002-7705-6913)
- Song Gao (ORCID: https://orcid.org/0000-0003-2361-3494)
- Eric Asare (ORCID: https://orcid.org/0009-0008-5621-7109)
- Shalom Emmanuel (ORCID: https://orcid.org/0009-0000-5190-1472)
Institutions
- Texas Southern University (US)
Publication Details
- Journal
- Metabolites
- Published
- 2024-10-22
- DOI
- https://doi.org/10.3390/metabo14110569
- Citations
- 1
- Primary Topic
- Synthesis of β-Lactam Compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.25
Funders
- Cancer Prevention and Research Institute of Texas
- National Institute on Minority Health and Health Disparities