Sodium-glucose cotransporter 2 inhibitors and cardiovascular events among patients with type 2 diabetes and low-to-normal body mass index: a nationwide cohort study

The protective effect of SGLT2 inhibitors on cardiovascular events among patients with type 2 diabetes appeared to decrease with lower BMI and was not significant among patients with low-to-normal BMI (< 25.0 kg/m2). These findings suggest the importance of considering BMI when initiating SGLT2 inhibitors.

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Publication Details

Journal
Cardiovascular Diabetology
Published
2024-10-22
DOI
https://doi.org/10.1186/s12933-024-02478-7
Citations
7
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
2.50
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article

Sodium-glucose cotransporter 2 inhibitors and cardiovascular events among patients with type 2 diabetes and low-to-normal body mass index: a nationwide cohort study

O. Kenrik Duru, Ryuichiro Yagi, Toshiaki Komura, Katherine R. Tuttle et al.
7 citations
Cardiovascular Diabetology
Diabetes Treatment and Management
2.50
article

Sodium-glucose cotransporter 2 inhibitors and cardiovascular events among patients with type 2 diabetes and low-to-normal body mass index: a nationwide cohort study

O. Kenrik Duru, Ryuichiro Yagi, Toshiaki Komura, Katherine R. Tuttle, Motoko Yanagita, Shingo Fukuma, Naoki Kondo, Motohiko Adomi, Kosuke Inoue, Yuichiro Mori
article en
7 citations

Abstract

The protective effect of SGLT2 inhibitors on cardiovascular events among patients with type 2 diabetes appeared to decrease with lower BMI and was not significant among patients with low-to-normal BMI (< 25.0 kg/m2). These findings suggest the importance of considering BMI when initiating SGLT2 inhibitors.

Cardiovascular DiabetologyVol. 23(1)
Boston University (US), Brigham and Women's Hospital (US), Harvard University (US), University of California, Los Angeles (US), Providence College (US), University of Washington (US), Kyoto University (JP), Inland Northwest Health Services (US)
Zero hunger
Openalex Percentile: Top 9%
Diabetes Treatment and Management
2.50
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Sodium-glucose cotransporter 2 inhibitors and cardiovascular events among patients with type 2 diabetes and low-to-normal body mass index: a nationwide cohort study — O. Kenrik Duru, Ryuichiro Yagi, et al. · Cardiovascular Diabetology (2024) | TGRS Research Map | TGRS