UBL3 Interacts with PolyQ-Expanded Huntingtin Fragments and Modifies Their Intracellular Sorting

These results suggest that UBL3 may play a significant role in the interaction and sorting of mHTT, contributing to the understanding of its potential implications in the pathophysiology of Huntington's disease.

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Publication Details

Journal
Neurology International
Published
2024-10-22
DOI
https://doi.org/10.3390/neurolint16060089
Citations
3
Primary Topic
Genetic Neurodegenerative Diseases
Type
article
Field-Weighted Citation Impact
0.80

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article

UBL3 Interacts with PolyQ-Expanded Huntingtin Fragments and Modifies Their Intracellular Sorting

Mitsutoshi Setou, Soho Oyama, Qing Zhai, Shuhei Aramaki et al.
3 citations
Neurology International
Genetic Neurodegenerative Diseases
0.80
article

UBL3 Interacts with PolyQ-Expanded Huntingtin Fragments and Modifies Their Intracellular Sorting

Mitsutoshi Setou, Soho Oyama, Qing Zhai, Shuhei Aramaki, Hengsen Zhang, Yusuke Takanashi, Mst. Afsana Mimi, Daita Kaneda, Tomoaki Kahyo, Yoshio Hashizume, Yashuang Ping, A. S. M. Waliullah, Rafia Ferdous, Md. Mahmudul Hasan, Yuna Tomochika, Bin Chen, Chi Zhang, Md. Shoriful Islam, Jing Yan, Shuyun Jiang
article en
3 citations

Abstract

These results suggest that UBL3 may play a significant role in the interaction and sorting of mHTT, contributing to the understanding of its potential implications in the pathophysiology of Huntington's disease.

Neurology InternationalVol. 16(6)
Jiangnan University (CN), Hamamatsu University School of Medicine (JP), Fukushimura Hospital (JP), Wuxi Fourth People's Hospital (CN), Choju Medical Institute (JP)
Nihon University, Japan Society for the Promotion of Science, Hospital Universiti Sains Malaysia, RIKEN
Openalex Percentile: Top 29%
Genetic Neurodegenerative Diseases
0.80
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