Infliximab versus Cyclophosphamide for Severe Behçet’s Syndrome

Among patients with severe Behçet's syndrome, induction therapy with infliximab had a superior complete response rate at 22 weeks and fewer adverse events than induction with cyclophosphamide. (Funded by the French Ministry of Health.).

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Publication Details

Journal
NEJM Evidence
Published
2024-10-22
DOI
https://doi.org/10.1056/evidoa2300354
Citations
29
Primary Topic
Ocular Diseases and Behçet’s Syndrome
Type
article
Field-Weighted Citation Impact
15.62
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article

Infliximab versus Cyclophosphamide for Severe Behçet’s Syndrome

Tristan Mirault, Matheus Vieira, Aurélie Plessier, Isabelle Melki et al.
29 citations
NEJM Evidence
Ocular Diseases and Behçet’s Syndrome
15.62
article

Infliximab versus Cyclophosphamide for Severe Behçet’s Syndrome

Tristan Mirault, Matheus Vieira, Aurélie Plessier, Isabelle Melki, Alban Redheuil, Matthieu Resche‐Rigon, A.C. Desbois, Georgina Maalouf, Élisabeth Maillart, Isabelle Koné‐Paut, Azeddine Dellal, P. Cacoub, Thomas Sené, F. Domont, S. Trad, Karim Sacré, Jean‐François Viallard, Julien Gaudric, Gaëlle Leroux, Adrien Mirouse, Mathieu Vautier, Aude Rigolet, Nicolas Noël, Amine Ghembaza, Yasmina Ferfar, Estibaliz Lazaro, Nicolas Mêlé, David Saadoun, A. Mékinian, Emmanuel Ribeiro, Laurent Chiche, Olivier Fain, Marc Lambert
article en
29 citations

Abstract

Among patients with severe Behçet's syndrome, induction therapy with infliximab had a superior complete response rate at 22 weeks and fewer adverse events than induction with cyclophosphamide. (Funded by the French Ministry of Health.).

NEJM EvidenceVol. 3(11)
Centre National de la Recherche Scientifique (FR), Inserm (FR), Université Paris Cité (FR), Université Paris-Saclay (FR), Hôpital Beaujon (FR), Saint Louis University Hospital (US), Centre Hospitalier Universitaire de Bordeaux (FR), Sorbonne Université (FR), Assistance Publique – Hôpitaux de Paris (FR), Centre François Baclesse (LU), Hôpital Européen Georges-Pompidou (FR), Hôpital Saint-Antoine (FR), Bordeaux Population Health (FR), Hôpital Saint-André (FR), Immunology from Concept and Experiments to Translation (FR), Hôpital Cardiologique du Haut-Lévêque (FR), Pitié-Salpêtrière Hospital (FR), Centre Hospitalier Sainte-Anne (FR), Centre de Recherche sur l'Inflammation (FR), Paris Cardiovascular Research Center (FR), Hôpital Ambroise-Paré (FR), Hôpital Bichat-Claude-Bernard (FR), Fondation pour l’innovation en Cadiométabolisme et Nutrition (FR), Hôpital Claude Huriez (FR), Groupe Hospitalier Intercommunal Le Raincy Montfermeil (FR), Bicêtre Hospital (FR), Immunologie - Immunopathologie - Immunothérapie (FR)
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Openalex Percentile: Top 0%
Ocular Diseases and Behçet’s Syndrome
15.62
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