Statistical analyses plan for “MAGnItude of cigarette substitutioN after initiation oF e-cigarettes and its ImpaCt on biomArkers of exposure and potenTial harm in dual users”: MAGNIFICAT trial

EC are increasingly adopted as a harm reduction strategy in CC smokers who wish to quit smoking, the outlined <b>Statistical Analysis Plan (SAP)</b> provides a robust approach to understand the impact of EC on CC use and to quantify the impact of dual use on clinical outcomes using BoPH. For statistical calculations we will use R software.