Significant individual variation in cardiac-cycle-linked cerebrospinal fluid production following subarachnoid hemorrhage
There is considerable inter-individual variation in net CSF flow rates following SAH. Net CSF flow in the Sylvian aqueduct differs markedly from the traditional ventricular CSF production rates of 0.30-0.40 mL/min in SAH patients, but less so in healthy subjects. Furthermore, the cardiac-cycle-linked net CSF flow rates in Sylvian aqueduct and CCJ suggest an important role of extra-ventricular CSF production.
Authors
- Erika Kristina Lindstrøm
- Geir Ringstad (ORCID: https://orcid.org/0000-0003-0919-4510)
- Per Kristian Eide (ORCID: https://orcid.org/0000-0001-6881-9280)
- Øivind Gjertsen (ORCID: https://orcid.org/0000-0002-3525-4399)
- Lars Magnus Valnes (ORCID: https://orcid.org/0000-0001-9283-5563)
- Ragnhild Undseth
Institutions
- Oslo University Hospital (NO)
- University of Oslo (NO)
- Institute for Energy Technology (NO)
- Sørlandet Hospital Arendal (NO)
Publication Details
- Journal
- Fluids and Barriers of the CNS
- Published
- 2024-10-22
- DOI
- https://doi.org/10.1186/s12987-024-00587-9
- Citations
- 5
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 1.34
Funders
- Universitetet i Oslo