Serum peroxiredoxin-4, a biomarker of oxidative stress, associates with new-onset chronic kidney disease: A population-based cohort study
This study supports the hypothesis that systemic oxidative stress, reflected by higher serum Prx4 levels, is significantly associated with the risk of developing CKD in the general population. These findings suggest that Prx4 could be a valuable biomarker for early risk stratification and prevention strategies in CKD management.
Authors
- Klaas Nico Faber (ORCID: https://orcid.org/0000-0001-8893-3312)
- Harry van Goor (ORCID: https://orcid.org/0000-0002-6670-1577)
- Ron T. Gansevoort (ORCID: https://orcid.org/0000-0002-3223-0906)
- Lyanne M. Kieneker (ORCID: https://orcid.org/0000-0002-8028-6488)
- Arno R. Bourgonje (ORCID: https://orcid.org/0000-0001-5754-3821)
- Sem Geertsema (ORCID: https://orcid.org/0000-0002-0335-5347)
- Stephan J. L. Bakker (ORCID: https://orcid.org/0000-0003-3356-6791)
- Robin P. F. Dullaart (ORCID: https://orcid.org/0000-0002-3844-5254)
- Amaal Eman Abdulle (ORCID: https://orcid.org/0000-0003-3766-2238)
- Gerard D. H. Dijkstra (ORCID: https://orcid.org/0000-0003-4563-7462)
- Paul Geertsema (ORCID: https://orcid.org/0000-0003-1376-9727)
- Sacha la Bastide‐van Gemert (ORCID: https://orcid.org/0000-0003-0666-6690)
Institutions
- University Medical Center Groningen (NL)
- University of Groningen (NL)
Publication Details
- Journal
- Redox Biology
- Published
- 2024-10-22
- DOI
- https://doi.org/10.1016/j.redox.2024.103408
- Citations
- 5
- Primary Topic
- Sulfur Compounds in Biology
- Type
- article
- Field-Weighted Citation Impact
- 1.47
Funders
- Nierstichting