Diagnostic incidence and pitfalls of rete testis hyperplasia and hyaline globules in a multi-institutional study of 348 testicular germ cell tumors
Rete hyperplasia and hyaline globules are not uncommon findings in the setting of germ cell tumors (including occurrences in various pure/mixed germ cell tumors) and can show striking overlap with yolk sac tumor. We hypothesize that these histologic pitfalls evolve secondary to testicular obstruction by the tumor mass. Recognition of and distinguishing this morphologic mimicry is fundamental to guide appropriate clinical management.
Authors
- Sean R. Williamson (ORCID: https://orcid.org/0000-0002-3898-1460)
- Robert Humble (ORCID: https://orcid.org/0000-0002-0509-9674)
- Mahmut Akgül (ORCID: https://orcid.org/0000-0003-0929-0940)
- Susan K. Potterveld (ORCID: https://orcid.org/0000-0001-7948-2337)
- Richard R. Pacheco (ORCID: https://orcid.org/0000-0002-9919-7290)
- Aysha Mubeen (ORCID: https://orcid.org/0000-0002-7309-3397)
- Ankur R. Sangoi (ORCID: https://orcid.org/0000-0003-0874-8964)
- Hailey L. Gosnell (ORCID: https://orcid.org/0000-0003-4952-2689)
Institutions
- Cleveland Clinic (US)
- University of New Mexico (US)
- Stanford Medicine (US)
- University of Iowa Health Care (US)
- Albany Medical Center Hospital (US)
Publication Details
- Journal
- American Journal of Clinical Pathology
- Published
- 2024-10-22
- DOI
- https://doi.org/10.1093/ajcp/aqae140
- Citations
- 1
- Primary Topic
- Testicular diseases and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.57