Synchrotron CT dosimetry for wiggler operation at reduced magnetic field and spatial modulation with bow tie filters

The Australian Synchrotron Imaging and Medical Beamline (IMBL) uses a superconducting multipole wiggler (SCMPW) source, dual crystal Laue monochromator and 135 m propagation distance to enable imaging and computed tomography (CT) studies of large samples with mono-energetic radiation. This study aimed to quantify two methods for CT dose reduction: wiggler source operation at reduced magnetic field strength, and beam modulation with spatial filters placed upstream from the sample. Transmission measurements with copper were used to indirectly quantify the influence of third harmonic radiation. Operation at lower wiggler magnetic field strength reduces dose rates by an order of magnitude, and suppresses the influence of harmonic radiation, which is of significance near 30 keV. Beam shaping filters modulate the incident beam profile for near constant transmitted signal, and offer protection to radio-sensitive surface organs: the eye lens, thyroid and female breast. Their effect is to reduce the peripheral dose and the dose to the scanned volume by about 10% for biological samples of 35-50 mm diameter and by 20-30% for samples of up to 160 mm diameter. CT dosimetry results are presented as in-air measurements that are specific to the IMBL, and as ratios to in-air measurements that may be applied to other beamlines. As CT dose calculators for small animals are yet to be developed, results presented here and in a previous study may be used to estimate absorbed dose to organs near the surface and the isocentre.

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Publication Details

Journal
Journal of Synchrotron Radiation
Published
2024-10-22
DOI
https://doi.org/10.1107/s1600577524008531
Citations
1
Primary Topic
Advanced Radiotherapy Techniques
Type
article
Field-Weighted Citation Impact
0.61

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article

Synchrotron CT dosimetry for wiggler operation at reduced magnetic field and spatial modulation with bow tie filters

Stewart Midgley, Nanette Schleich, A. W. Stevenson, Alex Merchant
1 citations
Journal of Synchrotron Radiation
Advanced Radiotherapy Techniques
0.61
article

Synchrotron CT dosimetry for wiggler operation at reduced magnetic field and spatial modulation with bow tie filters

Stewart Midgley, Nanette Schleich, A. W. Stevenson, Alex Merchant
article en
1 citations

Abstract

The Australian Synchrotron Imaging and Medical Beamline (IMBL) uses a superconducting multipole wiggler (SCMPW) source, dual crystal Laue monochromator and 135 m propagation distance to enable imaging and computed tomography (CT) studies of large samples with mono-energetic radiation. This study aimed to quantify two methods for CT dose reduction: wiggler source operation at reduced magnetic field strength, and beam modulation with spatial filters placed upstream from the sample. Transmission measurements with copper were used to indirectly quantify the influence of third harmonic radiation. Operation at lower wiggler magnetic field strength reduces dose rates by an order of magnitude, and suppresses the influence of harmonic radiation, which is of significance near 30 keV. Beam shaping filters modulate the incident beam profile for near constant transmitted signal, and offer protection to radio-sensitive surface organs: the eye lens, thyroid and female breast. Their effect is to reduce the peripheral dose and the dose to the scanned volume by about 10% for biological samples of 35-50 mm diameter and by 20-30% for samples of up to 160 mm diameter. CT dosimetry results are presented as in-air measurements that are specific to the IMBL, and as ratios to in-air measurements that may be applied to other beamlines. As CT dose calculators for small animals are yet to be developed, results presented here and in a previous study may be used to estimate absorbed dose to organs near the surface and the isocentre.

Journal of Synchrotron RadiationVol. 31(6)
Barwon Health (AU), Canberra Hospital (AU), Australian Synchrotron (AU), University of Otago (NZ)
Australian Nuclear Science and Technology Organisation, University of Otago, Australian Synchrotron, Barwon Health Foundation
Openalex Percentile: Top 30%
Advanced Radiotherapy Techniques
0.61
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