Is the identification of caseating granuloma in the intestine indicative of tuberculosis? a rare case of Crohn’s disease

In clinical practice, various forms of granulomas may indicate diverse underlying diseases, yet lack specificity. It is suggested that the presence of caseous granulomas should not be considered as a definitive exclusion criterion for the diagnosis when clinical, endoscopic, imaging and other histopathological features are consistent with CD. This study is the first report of caseous granulomas in CD without concomitant tuberculosis infection.

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Publication Details

Journal
Diagnostic Pathology
Published
2024-10-22
DOI
https://doi.org/10.1186/s13000-024-01566-2
Primary Topic
Diagnosis and treatment of tuberculosis
Type
article
Field-Weighted Citation Impact
0.00

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article

Is the identification of caseating granuloma in the intestine indicative of tuberculosis? a rare case of Crohn’s disease

Siqi Tao, Yan Chen, Wen Hu, Jinghong Xu et al.
2 links
Diagnostic Pathology
Diagnosis and treatment of tuberculosis
article

Is the identification of caseating granuloma in the intestine indicative of tuberculosis? a rare case of Crohn’s disease

Siqi Tao, Yan Chen, Wen Hu, Jinghong Xu, Keren Shen
article en

Abstract

In clinical practice, various forms of granulomas may indicate diverse underlying diseases, yet lack specificity. It is suggested that the presence of caseous granulomas should not be considered as a definitive exclusion criterion for the diagnosis when clinical, endoscopic, imaging and other histopathological features are consistent with CD. This study is the first report of caseous granulomas in CD without concomitant tuberculosis infection.

Diagnostic PathologyVol. 19(1)
National Clinical Research Center for Digestive Diseases (CN), Second Affiliated Hospital of Zhejiang University (CN), State Key Laboratory of Diagnosis and Treatment of Infectious Diseases, Zhejiang University (CN)
University of Chicago Medicine
Good health and well-being, Zero hunger
Openalex Percentile: Top 66%
Diagnosis and treatment of tuberculosis
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