Protective effects of saffron, safranal and crocin administration on vitamins (A, D, E, K) and protein carbonyl levels against CCI4- induced oxidative damage in rats
Objective: The possible effects of saffron and its active components on oxidative stress are known. Protein carbonyls (PCO), formed due to protein exposure to oxidizing agents, are a newly researched topic. In this study, it was aimed to determine, antioxidant fatsoluble vitamins (A, D, E, K) and PCO values after saffron, safranal and crocin administration with carbon tetrachloride (CCl4) in rats. Materials and Methods: Fifty-four Wistar albino male rats were randomly selected, and 9 groups of n=6 were formed. Vitamin levels in rat serum were determined by HPLC and PCO levels were determined by spectrophotometric method. Results: A significant difference (p
Authors
- Suat Ekin (ORCID: https://orcid.org/0000-0002-6502-5028)
- İrfan Bayram (ORCID: https://orcid.org/0000-0003-3093-4923)
- Ahmet BAKIR (ORCID: https://orcid.org/0000-0003-0797-285X)
- Damla Yıldız (ORCID: https://orcid.org/0000-0002-9489-3860)
- İbrahim Aras (ORCID: https://orcid.org/0000-0003-4911-3922)
- Gökhan Oto (ORCID: https://orcid.org/0000-0001-7310-7800)
Institutions
- Van Yüzüncü Yıl Üniversitesi (TR)
Publication Details
- Journal
- Marmara medical journal
- Published
- 2024-10-22
- DOI
- https://doi.org/10.5472/marumj.1571808
- Primary Topic
- Saffron Plant Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00