Brief communication: coagulation profiles of HIV positive patients on antiretroviral therapy (ART) at the Mampong Municipal Hospital, Ashanti-Region, Ghana: a case control study
This study aimed to ascertain how the current two ART regimens used in Ghana affected HIV patients' coagulation profiles. A case-control study was conducted on 102 HIV positive patients at the Mampong Municipal Hospital. Coagulation parameters measured showed APTT was normal in majority of ART-experienced participants but prolonged in majority of ART-naïve participants. The mean platelet count was significantly higher in ART-experienced participants. No significant differences were found between the coagulation profiles of ART-experienced patients on two different drug regimens. In conclusion, current ART can enhance the coagulation profiles in HIV-infected patients, by improving platelet count and APTT.
Authors
- Ekoutiamé Ahlin
- Abena Asefuaba Yalley (ORCID: https://orcid.org/0000-0003-2199-2558)
- Ransford Kyeremeh (ORCID: https://orcid.org/0000-0003-1490-2972)
- Akua K. Yalley (ORCID: https://orcid.org/0000-0002-7429-1707)
- Nicholas Israel Nii-Trebi (ORCID: https://orcid.org/0000-0001-5012-9564)
- Francis Opoku (ORCID: https://orcid.org/0000-0003-2674-6006)
Institutions
- Total (France) (FR)
- University of Ghana (GH)
- University of Konstanz (DE)
- University of Health and Allied Sciences (GH)
- Freie Universität Berlin (DE)
Publication Details
- Journal
- AIDS Research and Therapy
- Published
- 2024-10-22
- DOI
- https://doi.org/10.1186/s12981-024-00665-w
- Citations
- 1
- Primary Topic
- HIV/AIDS Research and Interventions
- Type
- article
- Field-Weighted Citation Impact
- 0.39
Funders
- Ghana National Petroleum Corporation