Overlap syndrome in liver diseases in children: case report and literature review
In children, autoimmune liver diseases can manifest in a variety of forms, including autoimmune hepatitis (AIH), primary sclerosing cholangitis (PSC), and the co-occurrence of AIH and PSC - the “overlap syndrome.” Early recognition of overlap syndrome is important. Diagnosis of sclerosing cholangitis largely depends on the cholangiographic picture showing single or multiple strictures with dilatation of the biliary tract. The problems of etiology, pathogenesis, diagnosis and treatment of overlap syndrome in children are shown. A clinical example of seronegative autoimmune hepatitis and sclerosing cholangitis as part of a cross syndrome in a child is given.
Authors
- K. A. Khasanova (ORCID: https://orcid.org/0000-0001-6926-3165)
- Г. В. Волынец (ORCID: https://orcid.org/0000-0002-5413-9599)
- E. S. Korochkina (ORCID: https://orcid.org/0000-0003-3537-6262)
- D. А. Skоbееv (ORCID: https://orcid.org/0000-0001-6446-9201)
- А. В. Никитин (ORCID: https://orcid.org/0000-0001-8837-9243)
- А. И. Хавкин (ORCID: https://orcid.org/0000-0001-7308-7280)
- Т. А. Скворцова (ORCID: https://orcid.org/0000-0002-6525-8665)
Institutions
- Sechenov University (RU)
- Pirogov Russian National Research Medical University (RU)
- Ministry of Health of the Russian Federation (RU)
- City Clinical Hospital (RU)
Publication Details
- Journal
- Experimental and Clinical Gastroenterology
- Published
- 2024-10-22
- DOI
- https://doi.org/10.31146/1682-8658-ecg-226-6-155-162
- Primary Topic
- Liver Diseases and Immunity
- Type
- article
- Field-Weighted Citation Impact
- 0.00