Assessment of metabolic indicators of the cardiovascular system in children with nephrotic syndrome

Objective: to evaluate the metabolic parameters of the cardiovascular system in nephrotic syndrome in children Material and methods: 110 children hospitalized with nephrotic syndrome in the nephrology department of the Samarkand Regional Children’s Multidisciplinary Medical Center were examined. Results: Renocardial syndrome with nephrotic syndrome develops in 64.8% of cases, the majority of patients are children 3-6 years of age (44.1%), with a predominance of boys (58.8%). In a cardiometric study in patients with nephrotic syndrome, renocardial syndrome is manifested by significant changes in metabolic and adaptation parameters: oxygen and lactate content - by 1.5 times, creatine phosphate - by 20%, tension index - by 4.8 times and vascular stiffness index - by 5.2 times. Conclusion: Deviation of cardiometry indicators in different age groups indicates a decrease in the intensity of blood circulation in organs and systems, indicating a significant load on the cardiovascular system in nephrotic syndrome.

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Publication Details

Journal
Experimental and Clinical Gastroenterology
Published
2024-10-22
DOI
https://doi.org/10.31146/1682-8658-ecg-226-6-96-100
Primary Topic
Electrolyte and hormonal disorders
Type
article
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article

Assessment of metabolic indicators of the cardiovascular system in children with nephrotic syndrome

B. A. Yuldashev, M. D. Murodova
Experimental and Clinical Gastroenterology
Electrolyte and hormonal disorders
article

Assessment of metabolic indicators of the cardiovascular system in children with nephrotic syndrome

B. A. Yuldashev, M. D. Murodova
article en

Abstract

Objective: to evaluate the metabolic parameters of the cardiovascular system in nephrotic syndrome in children Material and methods: 110 children hospitalized with nephrotic syndrome in the nephrology department of the Samarkand Regional Children’s Multidisciplinary Medical Center were examined. Results: Renocardial syndrome with nephrotic syndrome develops in 64.8% of cases, the majority of patients are children 3-6 years of age (44.1%), with a predominance of boys (58.8%). In a cardiometric study in patients with nephrotic syndrome, renocardial syndrome is manifested by significant changes in metabolic and adaptation parameters: oxygen and lactate content - by 1.5 times, creatine phosphate - by 20%, tension index - by 4.8 times and vascular stiffness index - by 5.2 times. Conclusion: Deviation of cardiometry indicators in different age groups indicates a decrease in the intensity of blood circulation in organs and systems, indicating a significant load on the cardiovascular system in nephrotic syndrome.

Experimental and Clinical Gastroenterology(6)
Samarkand State Medical Institute (UZ)
Good health and well-being
Openalex Percentile: Top 66%
Electrolyte and hormonal disorders
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