Onyx embolization for salvage hemostasis after intraoperative rupture

Video 1 shows three cases of intraoperative rupture during aneurysm coiling. Management of intraoperative aneurysm rupture is reviewed in brief, including reversal of anticoagulation/antiplatelets, intracranial pressure control, and rapid balloon deployment for control across the aneurysm neck. However, in all three cases, contrast extravasation continues despite aneurysm coiling, reversal of anticoagulation, and maximizing medical management. This is presumed to occur when the neck of the aneurysm is the site of rupture. We review the use of a salvage technique that can be considered as a last-ditch maneuver in these scenarios, which is deployment of Onyx liquid embolic (Medtronic). Onyx is the preferred liquid embolic for this use as it is cohesive instead of adhesive. The solvent used with Onyx, dimethyl sulfoxide, is also compatible with standard balloons.1 This is relevant because a balloon is needed both for control of hemorrhage during salvage embolization and for protection of the parent vessel from the embolic material. neurintsurg;16/12/1211/V1F1V1Video 1Demonstrating the technique of Onyx embolization for salvage hemostasis after intraoperative aneurysm rupture during coiling. Three example cases are shown.

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Publication Details

Journal
Journal of NeuroInterventional Surgery
Published
2024-10-20
DOI
https://doi.org/10.1136/jnis-2023-021402
Primary Topic
Intracranial Aneurysms: Treatment and Complications
Type
article
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article

Onyx embolization for salvage hemostasis after intraoperative rupture

Ryan P. Lee, Orlando Diaz-Daza, L. Fernando Gonzalez
Journal of NeuroInterventional Surgery
Intracranial Aneurysms: Treatment and Complications
article

Onyx embolization for salvage hemostasis after intraoperative rupture

Ryan P. Lee, Orlando Diaz-Daza, L. Fernando Gonzalez
article en

Abstract

Video 1 shows three cases of intraoperative rupture during aneurysm coiling. Management of intraoperative aneurysm rupture is reviewed in brief, including reversal of anticoagulation/antiplatelets, intracranial pressure control, and rapid balloon deployment for control across the aneurysm neck. However, in all three cases, contrast extravasation continues despite aneurysm coiling, reversal of anticoagulation, and maximizing medical management. This is presumed to occur when the neck of the aneurysm is the site of rupture. We review the use of a salvage technique that can be considered as a last-ditch maneuver in these scenarios, which is deployment of Onyx liquid embolic (Medtronic). Onyx is the preferred liquid embolic for this use as it is cohesive instead of adhesive. The solvent used with Onyx, dimethyl sulfoxide, is also compatible with standard balloons.1 This is relevant because a balloon is needed both for control of hemorrhage during salvage embolization and for protection of the parent vessel from the embolic material. neurintsurg;16/12/1211/V1F1V1Video 1Demonstrating the technique of Onyx embolization for salvage hemostasis after intraoperative aneurysm rupture during coiling. Three example cases are shown.

Journal of NeuroInterventional SurgeryVol. 16(12)
Houston Methodist (US), Johns Hopkins University (US), Johns Hopkins Medicine (US)
Life below water
Openalex Percentile: Top 71%
Intracranial Aneurysms: Treatment and Complications
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