An Observational Study of Acute Cholecystis in 50 Patients at a Tertiary Care Hospital in South Gujarat

Acute cholecystitis is an inflammatory condition of the gallbladder, commonly resulting from gallstone obstruction of the cystic duct. This obstruction leads to increased intraluminal pressure, ischemia, and bacterial infection, triggering an acute inflammatory response. Clinical manifestations include right upper quadrant pain, fever, nausea, and vomiting, with. Diagnosis is primarily confirmed through ultrasonography, revealing gallbladder wall thickening and pericholecystic fluid. Treatment involves supportive care, antibiotics, and cholecystectomy, which can be performed either urgently or electively based on the patient?s condition. Early intervention is crucial to prevent complications, such as gallbladder perforation, gangrene, and sepsis. This abstract reviews the pathophysiology, clinical presentation, diagnostic criteria, and treatment options for acute cholecystitis, emphasizing the importance of timely diagnosis and management for optimal patient outcomes.