Simple model of neurogliovascular unit activity with noradrenaline leading force

In this work we present a model of a neuroglivascular unit associated with a neuronal ensemble. We combine calcium dynamics in the astrocyte, the cascade of synthesis of arachidonic acid and its derivatives, as well as the activity of the network of inhibitory and excitatory neurons with changes in local blood flow. We add equations to the model for extracellular neurotransmitters such as GABA, glutamate, and norepinephrine. We show that the resulting model can exhibit different types of behavior, and also shows a significant connection between the functioning of the neural network and its supporting components.

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Publication Details

Published
2024-09-19
DOI
https://doi.org/10.1109/dcna63495.2024.10718403
Primary Topic
Heart Rate Variability and Autonomic Control
Type
article
Field-Weighted Citation Impact
0.00

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article

Simple model of neurogliovascular unit activity with noradrenaline leading force

Andrey Yu. Verisokin, Alexey Brazhe, Stanislav V. Lagosha, Darya V. Verveyko
Heart Rate Variability and Autonomic Control
article

Simple model of neurogliovascular unit activity with noradrenaline leading force

Andrey Yu. Verisokin, Alexey Brazhe, Stanislav V. Lagosha, Darya V. Verveyko
article en

Abstract

In this work we present a model of a neuroglivascular unit associated with a neuronal ensemble. We combine calcium dynamics in the astrocyte, the cascade of synthesis of arachidonic acid and its derivatives, as well as the activity of the network of inhibitory and excitatory neurons with changes in local blood flow. We add equations to the model for extracellular neurotransmitters such as GABA, glutamate, and norepinephrine. We show that the resulting model can exhibit different types of behavior, and also shows a significant connection between the functioning of the neural network and its supporting components.

Kursk State University (RU), Lomonosov Moscow State University (RU)
Ministry of Education and Science
Zero hunger
Openalex Percentile: Top 68%
Heart Rate Variability and Autonomic Control
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