Shank3 Overexpression Leads to Cardiac Dysfunction in Mice by Disrupting Calcium Homeostasis in Cardiomyocytes
This study revealed cardiac dysfunction in Shank3-overexpressing transgenic mice, potentially attributed to changes in Ca²⁺ homeostasis and contraction, with a notable reduction in troponin I.
Authors
- Tae Hee Ko (ORCID: https://orcid.org/0000-0002-9458-8452)
- Tran Nguyet Trinh (ORCID: https://orcid.org/0000-0003-4209-8248)
- Yeji Yang (ORCID: https://orcid.org/0000-0002-2994-4510)
- Yinhua Zhang (ORCID: https://orcid.org/0000-0002-3187-7142)
- Byeongil Yu (ORCID: https://orcid.org/0000-0001-7571-3273)
- Jong‐Il Choi (ORCID: https://orcid.org/0000-0001-6617-508X)
- Sun‐Hee Woo (ORCID: https://orcid.org/0000-0003-1444-3438)
- Kihoon Han (ORCID: https://orcid.org/0000-0002-5925-2152)
- Y. Kim (ORCID: https://orcid.org/0009-0009-2557-8945)
- Kwangmin Yoo (ORCID: https://orcid.org/0009-0007-2782-325X)
- Jungmin Choi (ORCID: https://orcid.org/0000-0002-8614-0973)
- Jin Young Kim (ORCID: https://orcid.org/0000-0002-0656-1269)
- Hyojin Kang (ORCID: https://orcid.org/0000-0002-3403-276X)
- Ruiying Ma
- Chunmei Jin (ORCID: https://orcid.org/0000-0002-0912-1031)
- Minju Lee (ORCID: https://orcid.org/0009-0001-7564-3516)
- Phuong Kim Luong (ORCID: https://orcid.org/0009-0003-8048-936X)
Institutions
- Chungnam National University (KR)
- Korea University (KR)
- Korea Basic Science Institute (KR)
- Korea Institute of Science & Technology Information (KR)
Publication Details
- Journal
- Korean Circulation Journal
- Published
- 2024-10-22
- DOI
- https://doi.org/10.4070/kcj.2024.0179
- Citations
- 1
- Primary Topic
- Congenital heart defects research
- Type
- article
- Field-Weighted Citation Impact
- 0.23
Funders
- National Research Foundation
- Korea University
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea