Construction of induced pluripotent stem cell line (CSBZZUi002-A) from the fibroblast cells of a healthy female

We recruited a healthy 44-year-old female and obtained her skin fibroblasts. Subsequently, the induced pluripotent stem cell line was successfully established using non-integrated reprogramming technology. The cell line had a normal karyotype and has been confirmed to have good pluripotency through the detection of pluripotency markers and detection of teratoma formation. This cell line can serve as an effective control for studying the cellular pathological mechanisms of other specific mutations.

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Publication Details

Journal
Stem Cell Research
Published
2024-10-20
DOI
https://doi.org/10.1016/j.scr.2024.103593
Primary Topic
Pluripotent Stem Cells Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Construction of induced pluripotent stem cell line (CSBZZUi002-A) from the fibroblast cells of a healthy female

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Construction of induced pluripotent stem cell line (CSBZZUi002-A) from the fibroblast cells of a healthy female

Jian‐Sheng Kang, Danhua Liu, Dian‐Dian Wang, Xiaohui Liu, Yingjie Zhang, Shuang Li, Wenxiu Li, Yue Wu, Xiao‐Yan Meng, Huifang Sun, Sen‐Miao Li, Peipei Liu
article en

Abstract

We recruited a healthy 44-year-old female and obtained her skin fibroblasts. Subsequently, the induced pluripotent stem cell line was successfully established using non-integrated reprogramming technology. The cell line had a normal karyotype and has been confirmed to have good pluripotency through the detection of pluripotency markers and detection of teratoma formation. This cell line can serve as an effective control for studying the cellular pathological mechanisms of other specific mutations.

Stem Cell ResearchVol. 81
First Affiliated Hospital of Zhengzhou University (CN)
Gender equality
Openalex Percentile: Top 83%
Pluripotent Stem Cells Research
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