Progression-free survival versus post-progression survival and overall survival in WHO grade 2 gliomas
We found a weak correlation between PFS and OS in WHO grade 2 gliomas, with the weakest correlation observed in oligodendrogliomas. Our analyses did not demonstrate any association between PFS and PPS. Critically, predictors of PFS are not necessarily predictors of OS. There is a need for validation of PFS as an endpoint in diffuse WHO grade 2 gliomas.
Authors
- Eddie de Dios
- Joshua D. Bernstock (ORCID: https://orcid.org/0000-0002-7814-3867)
- Lisa Millgård Sagberg (ORCID: https://orcid.org/0000-0001-7149-3082)
- Ole Solheim (ORCID: https://orcid.org/0000-0002-5954-4817)
- Timothy R. Smith (ORCID: https://orcid.org/0000-0003-1976-0766)
- Erik Thurin (ORCID: https://orcid.org/0000-0002-9631-3989)
- Øyvind Salvesen (ORCID: https://orcid.org/0000-0002-6145-8109)
- Vasileios K. Kavouridis (ORCID: https://orcid.org/0000-0002-2271-8588)
- Asgeir Store Jakola (ORCID: https://orcid.org/0000-0002-2860-9331)
- Noah Nawabi
- John L Kilgallon
Institutions
- Brigham and Women's Hospital (US)
- Harvard University (US)
- Norwegian University of Science and Technology (NO)
- Sahlgrenska University Hospital (SE)
- St Olav's University Hospital (NO)
- University of Gothenburg (SE)
Publication Details
- Journal
- Acta Oncologica
- Published
- 2024-10-20
- DOI
- https://doi.org/10.2340/1651-226x.2024.40845
- Citations
- 3
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.31