Quantification of white matter hyperintensities in type 1 diabetes and its relation to neuropathy and clinical characteristics
Our findings indicate increased burden of periventricular WMHs in diabetes which were associated to DPN severity and measurements reflecting neurodegeneration. Deep WMHs, often considered as chronic ischemic, were not significantly different. Mechanisms reflecting neurodegeneration and accelerated brain aging could be an overlooked aspect of peripheral and central neuropathy.
Authors
- Mimoza Gjela (ORCID: https://orcid.org/0000-0002-8329-3835)
- Johan Røikjer (ORCID: https://orcid.org/0000-0002-4578-1328)
- Suganthiya Santhiapillai Croosu (ORCID: https://orcid.org/0000-0003-0299-8962)
- Niels Ejskjær (ORCID: https://orcid.org/0000-0003-3749-3403)
- Jens Brøndum Frøkjær (ORCID: https://orcid.org/0000-0001-8722-0070)
- Yousef Yavarian
- Tine Maria Hansen (ORCID: https://orcid.org/0000-0002-6160-5519)
- Carsten Dahl Mørch (ORCID: https://orcid.org/0000-0001-6693-2028)
- Shahram Kianimehr
Institutions
- Aalborg University Hospital (DK)
- Aalborg University (DK)
Publication Details
- Journal
- Brain Research
- Published
- 2024-10-20
- DOI
- https://doi.org/10.1016/j.brainres.2024.149288
- Citations
- 7
- Primary Topic
- Botulinum Toxin and Related Neurological Disorders
- Type
- article
- Field-Weighted Citation Impact
- 2.58
Funders
- Aalborg Universitet
- Augustinus Fonden
- Aalborg Universitetshospital