The potential effect of d-cycloserine on the development of anxiety during exposure sessions in patients with agoraphobia

Our findings suggest potential short-term effects of DCS on anxiety during exposure. Long lasting and high degree of anxiety over exposure sessions is burdensome for the patients. Thus, modifications to reduce anxiety during exposure or to accelerate the learning process while maintaining the same treatment efficacy could be desirable. However, given the exploratory nature of the analyses, confirmatory studies testing the hypothesis of a decline of SUDS in agoraphobic patients are needed before confident conclusions can be made.

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Publication Details

Journal
Journal of Psychiatric Research
Published
2024-10-20
DOI
https://doi.org/10.1016/j.jpsychires.2024.10.018
Citations
2
Primary Topic
Sleep and related disorders
Type
article
Field-Weighted Citation Impact
1.02

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article

The potential effect of d-cycloserine on the development of anxiety during exposure sessions in patients with agoraphobia

Leopold Maria Lautenbacher, Jens Plag, Thomas Fydrich, Jennifer Mumm et al.
2 citations
Journal of Psychiatric Research
Sleep and related disorders
1.02
article

The potential effect of d-cycloserine on the development of anxiety during exposure sessions in patients with agoraphobia

Leopold Maria Lautenbacher, Jens Plag, Thomas Fydrich, Jennifer Mumm, Lena Pyrkosch, Andreas Ströhle, Lydia Fehm
article en
2 citations

Abstract

Our findings suggest potential short-term effects of DCS on anxiety during exposure. Long lasting and high degree of anxiety over exposure sessions is burdensome for the patients. Thus, modifications to reduce anxiety during exposure or to accelerate the learning process while maintaining the same treatment efficacy could be desirable. However, given the exploratory nature of the analyses, confirmatory studies testing the hypothesis of a decline of SUDS in agoraphobic patients are needed before confident conclusions can be made.

Journal of Psychiatric ResearchVol. 181
Humboldt-Universität zu Berlin (DE), Charité - Universitätsmedizin Berlin (DE)
Sonnenfeld Stiftung, Bundesministerium für Bildung, Wissenschaft, Forschung und Technologie
Openalex Percentile: Top 21%
Sleep and related disorders
1.02
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The potential effect of d-cycloserine on the development of anxiety during exposure sessions in patients with agoraphobia — Leopold Maria Lautenbacher, Jens Plag, et al. · Journal of Psychiatric Research (2024) | TGRS Research Map | TGRS