HIF1A/PCDH7 axis mediates fatty acid synthesis and metabolism to inhibit lung adenocarcinoma anoikis
Our findings demonstrated that the HIF1A/PCDH7 axis suppressed LUAD anoikis by promoting FA synthesis and metabolism. The FA synthesis pathway might be a key pathway regulated by PCDH7 in LUAD anoikis.
Authors
- Liyang Wei (ORCID: https://orcid.org/0000-0001-6531-7269)
- Xiaoyan Yang (ORCID: https://orcid.org/0000-0002-7591-7505)
- Qingfeng Zhang (ORCID: https://orcid.org/0000-0003-2246-8846)
- Kui Liu (ORCID: https://orcid.org/0009-0003-4882-5773)
Publication Details
- Journal
- Journal of Biochemical and Molecular Toxicology
- Published
- 2024-10-18
- DOI
- https://doi.org/10.1002/jbt.70001
- Citations
- 7
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 2.00