Use of immunotropic drugs in wound processes in different species of animals

In conditions of intensification of livestock farming, urbanization of society, accompanied by an increase in the number of productive and small domestic animals, changes in the conditions of their keeping, feeding, and exploitation, the number of non-communicable diseases is significantly increasing. Surgical diseases occupy a special place among them. In addition to accidental wounds, in some cases they are technologically widespread, especially in pig farming - castration, tail trimming, etc., accompanied by various kinds of complications. Classic measures of their treatment quite often do not give the expected effect, but due to the fact that any damage, including surgical damage, leads to the development of an immunodeficiency state. In such cases, the use of new techniques based on the use of immunotropic drugs is promising. It has been shown that the effectiveness of the wound-healing effect of thymogen and ribav is determined by the size of the defect, before or after the start of bioregulatory therapy, and treatment methods. It has been established that for wounds complicated by a fracture of the femur in outbred rats, the use of 5-day. A course of thymogen against the background of the use of kollapan-L causes more pronounced osteogenesis and ensures the formation of a more mature callus on the 45th day than in the control. Damage to the hooves of moose breeding stock reaches a 30% level. The main reason for this, in contrast to wild livestock, is the violation of housing and feeding. The inclusion of thymogen in complex therapy helps restore the clinical status of animals, as well as reduce the inflammatory reaction, endogenous and bacterial intoxication, and increase adaptive reactions, as evidenced by the dynamics of integral leukocyte indices. Application 5 days course of thymogen starting immediately after castration 5 months. boars in combination with etiotropic drugs helped to reduce the intensity of local reactions, the number of postoperative complications by four times, increased safety by 14.29%, average daily gains in live weight, and the production of meat products compared to the control of the highest category, in terms of cost when sold. The use of ribav was also effective, but less technologically advanced for mass processing of livestock.