Pharmacokinetics of the drug Amoxyantar in pigs

The article presents the results of pharmacokinetic studies of the drug Amoxiyantar in pigs. The results obtained indicate that amoxicillin is distributed throughout the tissues of animals, providing therapeutic concentrations in the studied dosage, ensuring effective distribution in the organs and tissues of the body of pigs, and also confirm the bioavailability of succinic acid with a high concentration in the blood plasma for an average of two hours. Based on the results of determining the dynamics of excretion of residual amounts of amoxicillin, it was detected in only one animal in the kidneys at a concentration of 54.9 μg/kg and in muscle tissue at a concentration of 25.2 μg/kg. In the remaining tissue samples of pigs obtained two days after application of the drug, as well as in all tissue samples of pigs obtained from the sixth day to the 18th day after application of the drug, amoxicillin was not detected.