Paraneoplastic neurological syndrome and its impact on the treatment outcomes of small‐cell lung cancer: A single‐center retrospective analysis

A total of 2.8% of patients had SCLC complicated by PNS, with poor PS observed. However, anticancer therapy led to an improvement in PS and comparable ORR, as well as PFS and OS similar to those observed in patients without PNS. Thus, anticancer therapy should be considered in patients with PNS.

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Publication Details

Journal
Thoracic Cancer
Published
2024-10-19
DOI
https://doi.org/10.1111/1759-7714.15472
Primary Topic
Autoimmune Neurological Disorders and Treatments
Type
article
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article

Paraneoplastic neurological syndrome and its impact on the treatment outcomes of small‐cell lung cancer: A single‐center retrospective analysis

Satoru Fujiwara, Kazuma Nagata, Keisuke Tomii, Atsushi Nakagawa et al.
1 links
Thoracic Cancer
Autoimmune Neurological Disorders and Treatments
article

Paraneoplastic neurological syndrome and its impact on the treatment outcomes of small‐cell lung cancer: A single‐center retrospective analysis

Satoru Fujiwara, Kazuma Nagata, Keisuke Tomii, Atsushi Nakagawa, Ryo Tachikawa, Yuki Sato, Ryosuke Hirabayashi, Chigusa Shirakawa
article en

Abstract

A total of 2.8% of patients had SCLC complicated by PNS, with poor PS observed. However, anticancer therapy led to an improvement in PS and comparable ORR, as well as PFS and OS similar to those observed in patients without PNS. Thus, anticancer therapy should be considered in patients with PNS.

Thoracic CancerVol. 15(34)
Kobe City Medical Center General Hospital (JP)
No poverty
Openalex Percentile: Top 71%
Autoimmune Neurological Disorders and Treatments
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