Gender Dysphoria in Turner Syndrome

Objectives: To report a case of a patient with Turner Syndrome (TS) experiencing gender dysphoria (GD), which refers to the psychological distress (lasting at least six months) that may result from an incongruence between the given and the experienced gender. Case Details: At sixteen, the patient realized she wanted to belong to the opposite gender, wishing to eliminate female secondary sexual characteristics. The patient developed a fleeting consideration of suicide and engaged in non-suicidal self-injury. Her mood symptoms worsened at nineteen, and she became more socially isolated as her academic performance declined. At 21, she did not present GD and did not want to transition gender anymore. Final Considerations: To the best of our knowledge, this is the first report of GD in a patient with the syndrome. It aligns with the understanding that gender identity is not only a social process but also a unique, individual construction. This case report highlights the importance of caution in transitional procedures since patients may need time to build their gender identity.