Establishing an induced pluripotent stem cell line (SDPHi006-A) from a healthy Chinese female donor represents an accomplishment
We isolated peripheral blood mononuclear cells (PBMCs) from a healthy female donor, and successfully converted into induced pluripotent stem cells (iPSCs) by using non-integrating episomal vectors. These iPSCs displayed a normal karyotype, expressed markers of pluripotency, and showed the capacity to differentiate into three germ layers in vitro, which could be utilized for future research endeavors.
Authors
- Yan Jin (ORCID: https://orcid.org/0000-0001-9844-6745)
- Jing Shao (ORCID: https://orcid.org/0000-0003-1308-8796)
- Chunhong Shao
Institutions
- People's Liberation Army 401 Hospital (CN)
- Shandong Provincial Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Stem Cell Research
- Published
- 2024-10-20
- DOI
- https://doi.org/10.1016/j.scr.2024.103590
- Primary Topic
- Pluripotent Stem Cells Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Department of Science and Technology of Shandong Province
- Natural Science Foundation of Shandong Province