Optimal timing for initiating androgen receptor signaling inhibitor therapy in patients with nonmetastatic castration-resistant prostate cancer: a multicenter collaborative study
Patients with rapid PSADT are at increased risk of early disease progression, suggesting that immediate treatment may be warranted. In addition, initiating therapy at a PSA level <5.4 ng/ml may be associated with improved patient outcomes in patients with low PSADT.
Authors
- Kenichi Hata (ORCID: https://orcid.org/0000-0002-6857-7354)
- Taro Igarashi (ORCID: https://orcid.org/0000-0002-5624-7614)
- Hiroki Yamada (ORCID: https://orcid.org/0000-0003-2987-7829)
- Shoji Kimura (ORCID: https://orcid.org/0000-0001-7194-5982)
- Fumihiko Urabe (ORCID: https://orcid.org/0000-0002-2599-8183)
- Kosuke Iwatani (ORCID: https://orcid.org/0000-0001-5428-852X)
- Wataru Fukuokaya (ORCID: https://orcid.org/0000-0003-1044-912X)
- Jun Miki (ORCID: https://orcid.org/0000-0002-4638-8640)
- Keiichiro Mori (ORCID: https://orcid.org/0000-0002-6147-6569)
- Masaya Murakami (ORCID: https://orcid.org/0000-0002-1268-6615)
- Takafumi Yanagisawa (ORCID: https://orcid.org/0000-0002-7410-0712)
- Kojiro Tashiro
- Shuhei Hara (ORCID: https://orcid.org/0009-0001-9842-3612)
- Takashi Ohtsuka (ORCID: https://orcid.org/0000-0002-8039-9159)
- Shunsuke Tsuzuki
- Yu Imai (ORCID: https://orcid.org/0000-0003-0971-4205)
- Akira Furuta (ORCID: https://orcid.org/0000-0001-7426-6395)
- Takahiro Kimura (ORCID: https://orcid.org/0000-0002-5673-1553)
- Koichi Aikawa (ORCID: https://orcid.org/0000-0003-0381-3368)
- Mahito Atsuta
- Brendan A. Yanada (ORCID: https://orcid.org/0000-0001-7962-8201)
- Yuya Iwamoto (ORCID: https://orcid.org/0009-0009-1396-3192)
- Yuma Goto
Institutions
- Jikei University School of Medicine (JP)
- The University of Melbourne (AU)
- Katsushika Medical Center (JP)
- Fujieda Municipal General Hospital (JP)
- Jikei University Kashiwa hospital (JP)
- Tsurugi Hospital (JP)
Publication Details
- Journal
- Japanese Journal of Clinical Oncology
- Published
- 2024-10-19
- DOI
- https://doi.org/10.1093/jjco/hyae146
- Citations
- 2
- Primary Topic
- Prostate Cancer Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.84