Diagnostic accuracy of ultrasonography and 99m-Technetium Sestamibi scintigraphy for the preoperative localization of Parathyroid Adenoma keeping histopathological findings as reference standard

Ultrasound despite its cost effectiveness has a lower sensitivity compared to 99m-Tc Sestamibi scintigraphy. Similarly, the sensitivity and overall accuracy of US and 99m-Tc Sestamibi scan when taken in combination is higher compared to either modality. It is thus recommended that the combination of these modalities should be employed to localize the adenomas accurately for surgery of the parathyroid gland for a better outcome.