Correlation between CT-based phenotypes and serum biomarker in interstitial lung diseases

Quantitative analysis of CT features and serum KL-6 levels ascertained a positive correlation between the two. In addition, the combination of reticulation and KL-6 shows potential for predicting hospitalizations of ILD patients due to respiratory causes. The combination of reticulation, focusing on phenotypic change in lung parenchyma, and KL-6, as an indicator of lung injury extent, could be helpful for monitoring and predicting the prognosis of various types of ILD.

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Publication Details

Journal
BMC Pulmonary Medicine
Published
2024-10-19
DOI
https://doi.org/10.1186/s12890-024-03344-8
Citations
6
Primary Topic
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Type
article
Field-Weighted Citation Impact
2.51

Funders

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article

Correlation between CT-based phenotypes and serum biomarker in interstitial lung diseases

Sung Goo Park, Beomsu Shin, Kyung Soo Lee, You Jin Oh et al.
6 citations
BMC Pulmonary Medicine
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
2.51
article

Correlation between CT-based phenotypes and serum biomarker in interstitial lung diseases

Sung Goo Park, Beomsu Shin, Kyung Soo Lee, You Jin Oh, Jonghun Kim, Ho Yun Lee
article en
6 citations

Abstract

Quantitative analysis of CT features and serum KL-6 levels ascertained a positive correlation between the two. In addition, the combination of reticulation and KL-6 shows potential for predicting hospitalizations of ILD patients due to respiratory causes. The combination of reticulation, focusing on phenotypic change in lung parenchyma, and KL-6, as an indicator of lung injury extent, could be helpful for monitoring and predicting the prognosis of various types of ILD.

BMC Pulmonary MedicineVol. 24(1)
Samsung Medical Center (KR), Gachon University Gil Medical Center (KR), Sungkyunkwan University (KR)
National Research Foundation, National Research Foundation of Korea, Ministry of Science and ICT, South Korea, Samsung, Institute for Information and Communications Technology Promotion
Good health and well-being
Openalex Percentile: Top 10%
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
2.51
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