Fecal glycoprotein 2 is a marker of gut microbiota dysbiosis and systemic inflammation

Fecal GP2 is a biomarker of gut microbiota dysbiosis and associated with increased systemic inflammation. The intestines may be more important as origin for GP2 than pancreatic acinar cells. Future studies need to investigate the potential clinical value in disease specific patient cohorts.

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Publication Details

Journal
Gut Pathogens
Published
2024-10-19
DOI
https://doi.org/10.1186/s13099-024-00657-1
Primary Topic
Gut microbiota and health
Type
article
Field-Weighted Citation Impact
0.00

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article

Fecal glycoprotein 2 is a marker of gut microbiota dysbiosis and systemic inflammation

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Gut microbiota and health
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Fecal glycoprotein 2 is a marker of gut microbiota dysbiosis and systemic inflammation

Frank Ulrich Weiß, Corinna Bang, Johannes Hertel, Henry Völzke, Peter Schierack, Dirk Roggenbuck, Matthias Nauck, Marcus Dörr, Matthias Sendler, Stefan Weiß, André Franke, Malte Rühlemann, Georg Homuth, Ali A. Aghdassi, Uwe Völker, Fabian Frost, Markus M. Lerch
article en

Abstract

Fecal GP2 is a biomarker of gut microbiota dysbiosis and associated with increased systemic inflammation. The intestines may be more important as origin for GP2 than pancreatic acinar cells. Future studies need to investigate the potential clinical value in disease specific patient cohorts.

Gut PathogensVol. 16(1)
Universitätsmedizin Greifswald (DE), Christian-Albrechts-Universität zu Kiel (DE), Brandenburg University of Technology Cottbus-Senftenberg (DE)
Deutsche Forschungsgemeinschaft
Good health and well-being
Openalex Percentile: Top 83%
Gut microbiota and health
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