Gestational organophosphate pesticide exposure and childhood cardiovascular outcomes
We observed heterogenous associations between gestational organophosphate pesticide exposure and pediatric cardiovascular health: an anti-atherogenic profile was observed for increases in ∑DEAP concentrations, and impairments in multiple aspects of cardiovascular health was observed for increases in ∑DMAP concentrations. PON1-161 and PON1-L55M single nucleotide polymorphisms modified associations for vascular and glycemic outcomes, respectively.
Authors
- Michiel A. van den Dries (ORCID: https://orcid.org/0000-0003-4874-0457)
- Anjoeka Pronk (ORCID: https://orcid.org/0000-0001-8652-2464)
- Vincent W. V. Jaddoe (ORCID: https://orcid.org/0000-0003-2939-0041)
- Suzanne Spaan
- Paige A. Bommarito (ORCID: https://orcid.org/0000-0002-4794-3570)
- Kelly K. Ferguson (ORCID: https://orcid.org/0000-0001-8467-3250)
- Romy Gaillard (ORCID: https://orcid.org/0000-0002-7967-4600)
- Henning W. Tiemeier (ORCID: https://orcid.org/0000-0002-4395-1397)
- Danielle R. Stevens (ORCID: https://orcid.org/0000-0002-4321-8355)
- Sophia M. Blaauwendraad
- Leonardo Trasande
Institutions
- National Institutes of Health (US)
- Universitat Pompeu Fabra (ES)
- Erasmus MC (NL)
- National Institute of Environmental Health Sciences (US)
- New York University (US)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- Environment International
- Published
- 2024-10-19
- DOI
- https://doi.org/10.1016/j.envint.2024.109082
- Citations
- 14
- Primary Topic
- Birth, Development, and Health
- Type
- article
- Field-Weighted Citation Impact
- 15.53
Funders
- Joint Programming Initiative A healthy diet for a healthy life
- Centres de Recerca de Catalunya
- Eastman Chemical Company
- European Commission
- ZonMw
- Erasmus Universiteit Rotterdam
- Generalitat de Catalunya
- Erasmus Medisch Centrum
- Nederlandse Organisatie voor Wetenschappelijk Onderzoek
- Ministerio de Ciencia e Innovación
- National Institutes of Health
- National Institute of Environmental Health Sciences