Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and suicidality: A replication study using reports to the World Health Organization pharmacovigilance database (VigiBase®)
Unlike our previous report with FAERS, a mixed pattern of ROR emerged in the WHO VigiBase with respect to suicidality and exposure to select GLP-RAs. Causation between GLP-1 RA exposure and suicidality (either increased or decreased) cannot be ascertained from ROR data.
Authors
- Angela T.H. Kwan (ORCID: https://orcid.org/0000-0003-4013-1112)
- Bing Cao (ORCID: https://orcid.org/0000-0001-5963-2676)
- Rodrigo B. Mansur (ORCID: https://orcid.org/0000-0002-3968-3297)
- Gia Han Le (ORCID: https://orcid.org/0000-0001-6457-0086)
- Joshua D. Rosenblat (ORCID: https://orcid.org/0000-0002-4773-2191)
- Roger Ho (ORCID: https://orcid.org/0000-0001-9629-4493)
- Roger S. McIntyre (ORCID: https://orcid.org/0000-0003-4733-2523)
- Kayla M. Teopiz (ORCID: https://orcid.org/0000-0001-8429-6563)
- Taeho Greg Rhee (ORCID: https://orcid.org/0000-0003-4961-3361)
- Sabrina Wong (ORCID: https://orcid.org/0009-0002-0928-3433)
Institutions
- Southwest University (CN)
- University of Toronto (CA)
- Yale University (US)
- Brain and Cognition Discovery Foundation (CA)
- National University Health System (SG)
Publication Details
- Journal
- Journal of Affective Disorders
- Published
- 2024-10-19
- DOI
- https://doi.org/10.1016/j.jad.2024.10.062
- Citations
- 38
- Primary Topic
- Treatment of Major Depression
- Type
- article
- Field-Weighted Citation Impact
- 17.02