A comparative study of traditional and molecular diagnostic methods for detection of gastrointestinal parasites in Nepalese migrants to the UK
Examination of a single faecal sample using qPCR alone showed superior or equivalent sensitivity to traditional methods for most GIP infections when both were compared to the reference standard. Combining molecular and traditional methods to analyse a single stool improved the detection rate for most studied parasites. This approach has value in settings where repeated sampling and/or faecal culture for helminths is impractical, but molecular diagnostics are available.
Authors
- Lucy Lamb (ORCID: https://orcid.org/0000-0001-5779-7207)
- Matthew K. O’Shea (ORCID: https://orcid.org/0000-0001-6414-8088)
- Tom Fletcher (ORCID: https://orcid.org/0000-0002-3712-415X)
- Nicholas J. Beeching (ORCID: https://orcid.org/0000-0002-7019-8791)
- L. Cunningham
- Stephen Woolley (ORCID: https://orcid.org/0000-0002-9385-8975)
- Emily R. Adams (ORCID: https://orcid.org/0000-0002-0816-2835)
- Jonathan W. D. Mason (ORCID: https://orcid.org/0000-0002-7640-7443)
- Jones Jj
Institutions
- University of Ulster (GB)
- Liverpool School of Tropical Medicine (GB)
- Queen Elizabeth Hospital Birmingham (GB)
- Royal Navy (GB)
- Birmingham Research Park (GB)
- Royal Victoria Hospital (GB)
- University of Birmingham (GB)
Publication Details
- Journal
- Journal of Infection
- Published
- 2024-10-19
- DOI
- https://doi.org/10.1016/j.jinf.2024.106324
- Citations
- 6
- Primary Topic
- Parasites and Host Interactions
- Type
- article
- Field-Weighted Citation Impact
- 3.09