Generation of Optimized Consensus Sequences for Hepatitis C virus (HCV) Envelope 2 Glycoprotein (E2) by a Modified Algorithm: Implication for a Pan-genomic HCV Vaccine
"Fitness" algorithm is capable of generating superior/optimum HCVE2 CSs for inclusion in a pan-genomic HCV vaccine and can be similarly used in CS generation for other highly variable antigens from other heterogenic pathogens.
Authors
- Katayoun Samimi‐Rad (ORCID: https://orcid.org/0000-0001-9705-2605)
- Farzin Roohvand (ORCID: https://orcid.org/0000-0002-9597-3555)
- Nasir Mohajel (ORCID: https://orcid.org/0000-0001-8883-4429)
- Reyhaneh Mohabati (ORCID: https://orcid.org/0000-0003-1524-7199)
- Reza Rezaei (ORCID: https://orcid.org/0000-0001-9652-9328)
- Kayhan Azadmanesh (ORCID: https://orcid.org/0000-0002-7165-9043)
- Mohammad Mehdi Ranjbar
Institutions
- Pasteur Institute of Iran (IR)
- Razi Vaccine and Serum Research Institute (IR)
- University of Tehran (IR)
- Agricultural Research & Education Organization (IR)
- Tehran University of Medical Sciences (IR)
Publication Details
- Journal
- Avicenna Journal of Medical Biotechnology
- Published
- 2024-10-19
- DOI
- https://doi.org/10.18502/ajmb.v16i4.16743
- Primary Topic
- Hepatitis C virus research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Pasteur Institute of Iran