5-Fluorouracil Effectively Depletes Tumor Induced Myeloid Derived Suppressor Cells in 4T1 Mammary Carcinoma Model
Findings show that 5-FU has inhibitory effects on MDSCs and tumor growth in 4T1 tumor model. So, more investigations are needed to study combination of 5-FU with immune based approaches to enhance the efficacy of cancer therapies.
Authors
- Mahdi Shabani
- Maedeh Alinejad
- Seyed Amir Jalali (ORCID: https://orcid.org/0000-0003-1174-4905)
- Mahmood Jeddi‐Tehrani (ORCID: https://orcid.org/0000-0002-8831-4711)
- Khadijeh Ramezani-Aliakbari
Institutions
- Bu-Ali Sina University (IR)
- Academic Center for Education, Culture and Research (IR)
- Shahid Beheshti University of Medical Sciences (IR)
Publication Details
- Journal
- Avicenna Journal of Medical Biotechnology
- Published
- 2024-10-19
- DOI
- https://doi.org/10.18502/ajmb.v16i4.16740
- Citations
- 2
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.48