Hepatic Sarcoidosis: A Case Report and Literature Review

Sarcoidosis is a granulomatous disease that can affect multiple organs, including the liver. We present a case of a 43-year-old male with hepatic sarcoidosis who presented with jaundice and pruritus. Laboratory findings showed mixed hyperbilirubinemia and elevated liver enzymes. Imaging revealed mediastinal lymphadenopathy and diffuse liver changes, raising suspicion for sarcoidosis. Elevated angiotensin-converting enzyme (ACE) levels and a liver biopsy confirmed the diagnosis. The patient was treated with ursodeoxycholic acid, leading to symptomatic improvement. This case highlights the importance of recognizing hepatic involvement in sarcoidosis and the potential role of ursodeoxycholic acid in its management.

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Publication Details

Journal
Cureus
Published
2024-10-19
DOI
https://doi.org/10.7759/cureus.71873
Primary Topic
Sarcoidosis and Beryllium Toxicity Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Hepatic Sarcoidosis: A Case Report and Literature Review

Eli A Zaher, Parth Patel, Mohamed Ebrahim
Cureus
Sarcoidosis and Beryllium Toxicity Research
article

Hepatic Sarcoidosis: A Case Report and Literature Review

Eli A Zaher, Parth Patel, Mohamed Ebrahim
article en

Abstract

Sarcoidosis is a granulomatous disease that can affect multiple organs, including the liver. We present a case of a 43-year-old male with hepatic sarcoidosis who presented with jaundice and pruritus. Laboratory findings showed mixed hyperbilirubinemia and elevated liver enzymes. Imaging revealed mediastinal lymphadenopathy and diffuse liver changes, raising suspicion for sarcoidosis. Elevated angiotensin-converting enzyme (ACE) levels and a liver biopsy confirmed the diagnosis. The patient was treated with ursodeoxycholic acid, leading to symptomatic improvement. This case highlights the importance of recognizing hepatic involvement in sarcoidosis and the potential role of ursodeoxycholic acid in its management.

CureusVol. 16(10)
Saint Joseph Hospital (US)
Zero hunger
Openalex Percentile: Top 75%
Sarcoidosis and Beryllium Toxicity Research
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