Control of grain size and weight by the RNA-binding protein EOG1 in rice and wheat

Grain size is one of the important yield traits in crops. Understanding the molecular and genetic mechanisms of grain-size control is important for yield improvement. Here, we report that the enhancer of GS2<sup>AA</sup> (EOG1) encodes an RNA-binding protein, which can bind mRNAs of several grain-size genes and influence their abundance. The eog1-1 mutant produces large and heavy grains by promoting cell proliferation in the spikelet hull. OsGSK3 physically interacts with and phosphorylates EOG1, thereby influencing the stability of EOG1. Genetic analyses support that EOG1 and OsGSK3 share overlapped function in grain size and weight control but does so independently of GS2. Notably, genome editing of wheat homologs TaEOG1A/B/D causes large and heavy grains. Thus, our findings identify a genetic and molecular mechanism whereby the OsGSK3-EOG1 module regulates grain size and weight in rice, suggesting that this pathway has the potential for grain-size improvement in key crops.

Authors

Institutions

Publication Details

Journal
Cell Reports
Published
2024-10-19
DOI
https://doi.org/10.1016/j.celrep.2024.114856
Citations
11
Primary Topic
Wheat and Barley Genetics and Pathology
Type
article
Field-Weighted Citation Impact
6.60
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Control of grain size and weight by the RNA-binding protein EOG1 in rice and wheat

Baolan Zhang, Yan Li, Bingyang Jiao, Yunhai Li et al.
11 citations
Cell Reports
Wheat and Barley Genetics and Pathology
6.60
article

Control of grain size and weight by the RNA-binding protein EOG1 in rice and wheat

Baolan Zhang, Yan Li, Bingyang Jiao, Yunhai Li, Penggen Duan, Xiahe Huang, Yun Zhou, Guanghui Guo, Hao Zhang, Yingchun Wang, Jinsong Xu, Limin Zhang, Wenjie Jiao, Huilan Wu, Huihui Liang
article en
11 citations

Abstract

Grain size is one of the important yield traits in crops. Understanding the molecular and genetic mechanisms of grain-size control is important for yield improvement. Here, we report that the enhancer of GS2<sup>AA</sup> (EOG1) encodes an RNA-binding protein, which can bind mRNAs of several grain-size genes and influence their abundance. The eog1-1 mutant produces large and heavy grains by promoting cell proliferation in the spikelet hull. OsGSK3 physically interacts with and phosphorylates EOG1, thereby influencing the stability of EOG1. Genetic analyses support that EOG1 and OsGSK3 share overlapped function in grain size and weight control but does so independently of GS2. Notably, genome editing of wheat homologs TaEOG1A/B/D causes large and heavy grains. Thus, our findings identify a genetic and molecular mechanism whereby the OsGSK3-EOG1 module regulates grain size and weight in rice, suggesting that this pathway has the potential for grain-size improvement in key crops.

Cell ReportsVol. 43(11)
Henan University (CN), Chinese Academy of Sciences (CN), State Key Laboratory of Plant Genomics (CN), Institute of Genetics and Developmental Biology (CN)
Zero hunger
Openalex Percentile: Top 4%
Wheat and Barley Genetics and Pathology
6.60
DOIOpen Access PDFOpenAlex
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.