A High-Intensity versus Moderate-Intensity Exercise Training Programme in Alpha-1 Antitrypsin Deficiency-Related COPD (IMAC): A Randomized, Controlled Trial
Although HIT and MIT were equally effective by improving exercise capacity, quality of life, and dyspnoea in homozygous AATD, HIT may show advantages over MIT, if anxiety or depression symptoms were present. The goal should be personalized training based on the patient's personal preference in order to achieve long-term adherence.
Authors
- Wolfgang Hitzl (ORCID: https://orcid.org/0000-0002-7696-1479)
- Andreas Rembert Koczulla (ORCID: https://orcid.org/0000-0002-5884-3006)
- Clancy John Dennis
- Daniela Kroll
- Tessa Schneeberger (ORCID: https://orcid.org/0009-0003-3638-6478)
- Rainer Gloeckl (ORCID: https://orcid.org/0000-0002-2741-2748)
- Inga Jarosch (ORCID: https://orcid.org/0000-0002-7147-7418)
- Klaus Kenn
Institutions
- Philipps University of Marburg (DE)
- Paracelsus Medical University (AT)
- German Center for Lung Research (DE)
- Schön Klinik Berchtesgadener Land (DE)
Publication Details
- Journal
- Respiration
- Published
- 2024-10-19
- DOI
- https://doi.org/10.1159/000541448
- Citations
- 2
- Primary Topic
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Type
- article
- Field-Weighted Citation Impact
- 0.84