Amyloid deposition and its association with depressive symptoms and cognitive functions in late-life depression: a longitudinal study using amyloid-β PET images and neuropsychological measurements
These findings suggest distinct mechanisms may underlie amyloid deposition in neurodegenerative changes associated with depression. While amyloid burden in specific brain regions negatively correlated with somatic anxiety, it showed no significant correlation with the severity of depression or overall cognitive function.
Authors
- Hong Jin Jeon (ORCID: https://orcid.org/0000-0002-6126-542X)
- Yoo Jin Jang (ORCID: https://orcid.org/0000-0001-9945-3541)
- Hyun‐Soo Kim (ORCID: https://orcid.org/0000-0001-7190-0362)
- Mi Jin Park
- Kiwon Kim (ORCID: https://orcid.org/0000-0001-7594-0142)
- Joon‐Kyung Seong (ORCID: https://orcid.org/0000-0001-6291-5415)
- Jeong-Hyeon Shin
Institutions
- Korea University (KR)
- Samsung (South Korea) (KR)
- Samsung Medical Center (KR)
- Kangbuk Samsung Hospital (KR)
- Bio-Medical Science (South Korea) (KR)
- The Catholic University of Korea Seoul St. Mary's Hospital (KR)
- Korea Testing Laboratory (KR)
- Dong-A University (KR)
- Sungkyunkwan University (KR)
- Catholic University of Korea (KR)
Publication Details
- Journal
- Alzheimer s Research & Therapy
- Published
- 2024-10-19
- DOI
- https://doi.org/10.1186/s13195-024-01562-0
- Citations
- 6
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 2.31
Funders
- Ministry of Trade, Industry and Energy
- Korea Health Industry Development Institute
- Samsung