Association of hyperactivated transposon expression with exacerbated immune activation in systemic lupus erythematosus
Our findings suggest that TE expression may serve as a crucial mediator in maintaining the activation of interferon pathways, acting as an endogenous source of nucleic acid stimulators in SLE patients.
Authors
- Xiao Dang (ORCID: https://orcid.org/0000-0001-6609-2807)
- Huidong Su
- Caicai Zhang (ORCID: https://orcid.org/0000-0002-7687-0518)
- Wanling Yang (ORCID: https://orcid.org/0000-0003-0063-6327)
- Feng Hong (ORCID: https://orcid.org/0000-0001-5120-3519)
- Xinxin Chen (ORCID: https://orcid.org/0000-0001-6521-5983)
- Jing Yang (ORCID: https://orcid.org/0000-0001-9764-5136)
- Qingyun Wang (ORCID: https://orcid.org/0009-0007-5606-8505)
- Yao Lei (ORCID: https://orcid.org/0000-0002-4299-8011)
- Chun Hing She
- Xingtian Yang
Institutions
- University of Hong Kong (HK)
Publication Details
- Journal
- Mobile DNA
- Published
- 2024-10-19
- DOI
- https://doi.org/10.1186/s13100-024-00335-8
- Citations
- 5
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 2.35
Funders
- National Key Research and Development Program of China