Jiajiejian gel ameliorates thyroid nodules through regulation of thyroid hormones and suppression of the (IL-6, TNF-α, IL-1β)/JAK2/STAT3/VEGF pathway
This study indicates that JJJG efficiently ameliorates thyroid nodules by regulating the levels of FT3, FT4 and TSH in serum and suppressing (IL-6, TNF-α, IL-1β)/JAK2/STAT3/VEGF pathway in thyroid tissue, providing a potential therapeutic approach for thyroid nodules.
Authors
- Changlin Wang (ORCID: https://orcid.org/0000-0002-2353-6022)
- Mingqi Qiao (ORCID: https://orcid.org/0000-0001-7310-1206)
- Yinghui Guo (ORCID: https://orcid.org/0000-0003-4143-1600)
- Dongmei Gao (ORCID: https://orcid.org/0000-0003-3442-5704)
- Xiangju Gao (ORCID: https://orcid.org/0009-0003-5617-4042)
- Chunhong Song
- Jieqiong Wang (ORCID: https://orcid.org/0000-0001-8907-5778)
Institutions
- Shandong University of Traditional Chinese Medicine (CN)
- Jinan Central Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2024-10-18
- DOI
- https://doi.org/10.3389/fphar.2024.1483686
- Citations
- 5
- Primary Topic
- Thyroid Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.79
Funders
- Shandong University
- National Natural Science Foundation of China