Immune-related toxic epidermal necrolysis affecting trachea mucosal epithelium: a case report and literature review
The mucocutaneous toxicity induced by PD-1 monoclonal antibodies is not limited to the surface of the skin but also in deep mucosal layers, potentially leading to life-threatening complications. Therefore, when using PD-1 monoclonal antibodies, clinicians should closely monitor adverse events and apply appropriate treatments as soon as possible to prevent severe complications.
Authors
- Bicheng Zhang (ORCID: https://orcid.org/0000-0002-6759-6748)
- Mingbo Zhang (ORCID: https://orcid.org/0000-0001-7342-9834)
- Xia Gao (ORCID: https://orcid.org/0009-0008-5171-4835)
- Jun Wang (ORCID: https://orcid.org/0000-0001-8930-258X)
- Yang Fu (ORCID: https://orcid.org/0000-0003-1023-2449)
- Yuxiao Song
Institutions
- Hubei University of Chinese Medicine (CN)
- Wuhan University (CN)
- Renmin Hospital of Wuhan University (CN)
- Affiliated Hospital of Shandong University of Traditional Chinese Medicine (CN)
- Shandong First Medical University (CN)
- Xiangyang Hospital of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2024-10-18
- DOI
- https://doi.org/10.3389/fphar.2024.1454015
- Citations
- 4
- Primary Topic
- Drug-Induced Adverse Reactions
- Type
- article
- Field-Weighted Citation Impact
- 1.79
Funders
- National Natural Science Foundation of China
- Chinese Society of Clinical Oncology